Nasal Steroids
Spring has finally arrived and with it, all of the allergy
symptoms we know so well: itchy watery eyes, sneezing, nasal
congestion, runny nose and cough. You're not alone if you suffer
from allergies. As many as 15-25% or 40 million Americans have
allergies to indoor and outdoor allergens. Springtime means tree
allergies. The yellow dust that will cover our cars later this
month is due to oak trees, besides other important trees such as
maple and elm. Spring is followed by the summer grasses and fall
weeds. Remember that allergies are genetic in origin (i.e., runs
in family) and environmental as well. Therefore, whether a child
or adult, if allergies run in your family and you happen to live
in the Mid-Atlantic region where allergies can be severe, you
may over time develop allergy symptoms.
So much for the bad news. The good news is that our
understanding of the mechanisms of allergies in addition to
treatment options have increased considerably over the past 5-10
years. We now know that inflammation is primarily responsible
for the symptoms of allergies. Inflammation occurs when cells in
the tissues, and cells in the blood which migrate into tissues,
react to allergens and release potent chemical mediators such as
histamine. Histamine in turn causes itching, swelling, mucus
production and drainage. Furthermore, inflammation from
allergies, if left untreated, is now known to cause sinusitis
(infection of the sinuses) and even asthma, which can be life
threatening. Sinusitis in turn can also cause asthma. It is
therefore very important to control and if possible, eliminate
inflammation.
Steroids are the best medication available to control and
eliminate inflammation (shown below). Not all steroids are the
same. Indeed, steroids differ in their ability to penetrate
tissue, remain active in the tissue (i.e., half life) and reduce
inflammation. Studies indicate that Rhinocort, Flonase and
Nasonex are the most potent nasal steroids, and in all cases,
steroids control nasal symptoms better than oral antihistamines.
The newest nasal steroid, Rhinocort Aqua, has the additional
advantage of being fragrance free, which may be helpful for
those patients having nasal irritation from fragrance. Most
important, recent studies now show that inhaled steroids do not
cause any significant growth reduction in children, and are
therefore very safe to use.
NASAL STEROID SPRAYS
|
Name
|
Steroid
|
Available As
|
Dosing
|
|
Rhinocort
|
Budesonide
|
Aerosol, Aqueous (Aqua)
|
1-2 sprays once or twice daily
|
|
Flonase
|
Fluticasone
|
Aqueous
|
1-2 sprays once or twice daily
|
|
Nasonex
|
Mometasone
|
Aqueous
|
1-2 sprays once or twice daily
|
|
Nasacort
|
Triamcinolone
|
Aerosol, Aqueous(Aq)
|
1-2 sprays once or twice daily
|
|
Nasalide
|
Flunisolide
|
Aqueous
|
1-2 sprays twice daily
|
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